The Future Insight Prize 2020, a research grant worth € 1 million, was awarded to Professor Stephan Sieber and his research group at the Technical University of Munich, Germany. This team is working on ways to overcome antibiotic resistance to bacteria. Antimicrobial resistance poses a major risk for humanity because it threatens medical advances that researchers and developers are pursuing around the globe. The Covid-19 pandemic illustrates the urgent need for scientific breakthroughs in the area of pandemic prevention in addition to addressing the root causes of wild pathogens that come into contact with humans.